Type

A single BTF-cone-plate unit (28 cm² cell culture surface with constant shear stress) with computerized shear stress control, different shear stress profiles of 0 – ca. 100 dyn/cm².

Add-on
microscope, impedance spectroscopy, temperature control, mass flow controller

Advantages

  1. Generation of highly precise shear stress profiles: e.g. used as calibration tool in fluid-dynamics; shear stress regulation from 0 to about 100 dyn/cm2.
  2. Free adjustable flow profiles: provides regulated constant, pulsatile, oscillatory, and free adjustable flow profiles
  3. Easy to handle setup for lifelong use
  4. Customer specific setups: single BTF-units, multi channel setups, combined with or without control unit and/or software and/or impedance spectroscopy, usable also in BSL 4 labs
  5. Transparency: Online observation of the investigated system, e.g. living cells
  6. Long-term experiments with continuous medium exchange
  7. Computer-regulated bioreactor: flexible software for easy data navigation, classification, and image acquisition to allow time-resolved image analyses
  8. Multi channel setup: Investigations of manipulated and control cells of the same passage at different levels of shear stress within the same period of time
  9.  Electrophysiological measurements (impedance spectroscopy): Barrier function of sheet forming cell layers (e.g. TER: transcellular electrical resistance of epithelial or endothelial cells)
  10. Sealed chambers for cell culture (e.g. infections, hypoxia)