Life Sciences

  • Research fundamentals for biology and medicine, as well as clinical research
  • Mechanical stimulation of cultivated cells through shear stress, specifically: cell migration, elongation, and signal transduction
  • Cell-to-cell interactions on cultivated cell layers (epithelial and endothelial)
  • Barrier functionality measurements under shear stress (impedance spectroscopy) and physiological, pathological, conditions
  • Influence of shear stress on viral/bacterial infections, host reactions (leukocyte adhesion) and emigration of tumor cells through cell layers
  • Testing equipment used in pharmaceutical research to evaluate potentially useful pharmaceutical products under standardized conditions: screening of cells originating from the same source, the same pathways, and the same thickness under many simultaneous testing conditions (concentration, shear stress profile, control conditions)
  • Stem cell research
  • Wound healing assay

Biotechnology

  • Cell-substrate interactions
  • Cell adhesion measurements and cell release kinetics in relation to biomaterials or immobilized/absorbing proteins
  • Protein absorption measurements using the method of TIRF analysis

Micro Fluid Dynamics

  • Calibrating equipment of wall shear stress sensors
  • Calibration of MPS3 (Micro Pillar Shear Stress Sensor) in nano- and microfluid dynamics (S. Große, C. Brücker, W. Schröder, ACCESS e.V. Aachen)